MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a Selective E Prostanoid Receptor 4 Antagonist, Relieves Joint Inflammation and Pain in Rodent Models of Rheumatoid and Osteoarthritis
Patsy Clark, Steven E. Rowland, Danielle Denis, Marie-Claude Mathieu, Rino Stocco, Hugo Poirier, Jason Burch, Yongxin Han, Laurent Audoly, Alex G. Therien and Daigen Xu
- DOI:
http://dx.doi.org/10.1124/jpet.107.134510
JPET May 2008 vol. 325 no. 2 425-434
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